Skip to main content

Featured post

Otitis Externa and Otinova

  Otitis Externa and Otinova: A Practical, No-Nonsense Guide If your ear suddenly feels itchy, sore, blocked, or painful after swimming or showering, you may be dealing with otitis externa —often called “swimmer’s ear.” The good news: most cases are very treatable with the right early steps. This guide explains what otitis externa is, why it happens, where Otinova fits in, and when to escalate quickly. What is otitis externa? Otitis externa is inflammation (and sometimes infection) of the skin lining the external ear canal. It commonly presents with: Ear pain (often worse when touching or pulling the outer ear) Itching Fullness/blockage Reduced hearing from swelling/debris Sometimes watery discharge Otinova’s own instruction documents describe it as treatment for ear canal inflammation/eczema (swimmer’s ear). Why does it happen? The ear canal is protected by a mildly acidic environment and a skin barrier. Otitis externa tends to flare ...

Why Some People Can't Stop Coughing

 



Understanding Refractory Chronic Cough: What You Need to Know

 

Have you ever faced a cough that simply refuses to subside?

 

While most coughs resolve independently, some persist for an unacceptable length of time—weeks, months, or even years. This condition is known as refractory chronic cough (RCC), and it is a significant issue that demands attention in the medical community, especially among specialists in ear, nose, and throat (ENT) care.

 

In this blog post, we will clearly outline what RCC is, why it occurs, and the most promising treatments available to those suffering from relentless coughing.

  

What is Refractory Chronic Cough?

 

A chronic cough is defined as one that lasts longer than eight weeks in adults. For many individuals, it is associated with conditions such as asthma, allergies, acid reflux, or certain medications. However, there are instances where the cough continues even after these underlying causes have been effectively addressed.

 This persistent and unexplained coughing is referred to as refractory chronic cough (RCC), which impacts as many as 46% of patients referred to specialists. RCC is not just a nuisance; it can severely disrupt breathing, interfere with daily activities, degrade sleep quality, and hinder social interactions.

 

It is critical for patients to seek appropriate evaluation and treatment for this distressing condition.

Why Does RCC Happen?

Coughing is a natural reflex that helps clear irritants from our airways. However, in RCC, this reflex becomes overly sensitive, causing a person to cough even when there’s no real need to. Researchers believe that both the nerves in the throat and the brain’s response to cough signals play a role in this hypersensitivity. Factors such as airway inflammation, nerve dysfunction, and central sensitization (similar to chronic pain conditions) can contribute to RCC. Additionally, exposure to pollutants, infections, or prior respiratory illnesses can make the airway more susceptible to developing RCC.


Symptoms and Impact of RCC

People with RCC often experience persistent coughing fits triggered by talking, laughing, exposure to certain smells, or temperature changes. The condition can lead to complications such as voice strain, throat pain, headaches, sleep disturbances, and even urinary incontinence due to the repetitive pressure from coughing. The social impact can also be significant, as people may avoid public places due to embarrassment or discomfort caused by their persistent cough.

New Advances in RCC Treatment

  1. Neuromodulators – Medications like amitriptyline and gabapentin help calm overactive nerves that trigger chronic coughing. Studies show that these drugs can significantly reduce symptoms in many patients. However, they may cause side effects such as drowsiness and dizziness, so careful dosage adjustments are needed.
  2. Superior Laryngeal Nerve (SLN) Block – This involves injecting a local anesthetic and steroid near a key nerve in the throat. It has shown promising results in reducing cough severity and frequency, with some patients experiencing relief lasting several months.
  3. Behavioral Cough Suppression Therapy (BCST) – Speech therapists teach patients techniques to control their cough reflex, including breathing exercises, vocal hygiene, and habit reversal strategies. Many people experience lasting improvement after therapy. This approach is particularly beneficial because it does not involve medication, making it a safer option for many patients.
  4. Capsaicin Therapy – Surprisingly, exposure to capsaicin (the compound that makes chili peppers spicy) in controlled doses can help desensitize the cough reflex over time. This method is still being studied, but early results suggest it may be effective in reducing cough hypersensitivity.
  5. Laryngopharyngeal Reflux (LPR) Management – Since acid reflux can contribute to RCC, new treatments like alginate therapy (which forms a protective barrier in the stomach) are being explored alongside traditional acid-reducing medications. Lifestyle changes, such as dietary modifications and avoiding late-night meals, can also help manage reflux-related cough.
  6. P2X3 Antagonists – A new class of medications targeting the P2X3 receptor, which is involved in the cough reflex, is being studied. Early trials have shown that these drugs may help reduce RCC symptoms, providing another potential treatment avenue.

What This Means for You


Coughing is a natural reflex that helps clear irritants from our airways. However, in RCC, this reflex becomes overly sensitive, causing a person to cough even when there’s no real need to. Researchers believe that both the nerves in the throat and the brain’s response to cough signals play a role in this hypersensitivity. Factors such as airway inflammation, nerve dysfunction, and central sensitization (similar to chronic pain conditions) can contribute to RCC. Additionally, exposure to pollutants, infections, or prior respiratory illnesses can make the airway more susceptible to developing RCC.

People with RCC often experience persistent coughing fits triggered by talking, laughing, exposure to certain smells, or temperature changes. The condition can lead to complications such as voice strain, throat pain, headaches, sleep disturbances, and even urinary incontinence due to the repetitive pressure from coughing. The social impact can also be significant, as people may avoid public places due to embarrassment or discomfort caused by their persistent cough.


The good news is that doctors are finding better ways to treat RCC. Here are some of the latest approaches:


If you or someone you know has a chronic cough that doesn’t improve with standard treatments, it’s important to see a specialist. ENT doctors and pulmonologists (chest physicians) now have a growing range of options to help manage RCC. The key is to undergo a thorough evaluation to rule out underlying conditions and explore the best treatment plan tailored to individual needs.

With ongoing research, treatment for refractory chronic cough is becoming more effective, improving the quality of life for many patients. By spreading awareness about RCC, we can help those affected find the relief they need.


Have you dealt with a persistent cough? Share your experience in the comments below!


Mr Gaurav Kumar

Consultant Ear Nose Throat Surgeon


Book Appointment

Book Online


07494914140




Follow on Instagram










Popular Post

Coblation Tonsillectomy

Hi Guys, Let us talk about your tonsils and adenoids. Tonsils and adenoids are part of the immune system and help fight germs. Sometimes these tissues become infected and is called tonsillitis. When you have tonsillitis, you can feel sore to eat and drink, have the temperature, and can even have difficulty in breathing. This can be treated by a procedure called Tonsillectomy. Mr Kumar may advise you to have your tonsils removed if you have tonsil stones, if your airway is blocked due to large tonsils making you choke at night ie sleep apnoea or one tonsil is bigger than other. Tonsillectomy can be done by the traditional techniques using cold steel, electrocautery or coblation.  Cold steel and elctrocautery has moderate to severe pain in postoperative period. With new coblation technique, post operative pain is very low leading to quicker recovery.  Coblation is an advanced technology that combines gentle radiofrequency energy with natural saline — to quickly, and safely r...

What are different types of nasal sprays?

Nasal sprays are a popular form of medication for treating nasal allergy symptoms. They are sprayed directly into the nose to target the symptoms without affecting the rest of the body. There are many types of nasal sprays available, both prescription and over-the-counter. Here is a quick guide to the different types: Nasal Steroid Sprays: These are usually one of the first-line allergy therapies. They decrease inflammation within the nasal passages and relieve nasal congestion, sneezing, watery eyes, and runny nose. Many of these sprays are available over the counter. Some common generic and brand names include Budesonide, Ciclesonide, Fluticasone, Flunisolide, Mometasone, Rhinocort, Omnaris, Zetonna, Flonase, Nasonex, Nasacort, Xhance, Beconase, Nasarel, Qnasl, Vancenase, Veramyst, and Zetonna Nasal Decongestant Sprays: These sprays temporarily relieve nasal congestion by constricting the blood vessels in the nose, reducing nasal swelling and congestion. They are available over the...

Earbuds vs Over-Ears: Which One Is Silently Damaging Your Hearing?

Headphones are no longer an occasional accessory—they’re part of daily life. From early-morning podcasts to late-night playlists, our ears are spending more time under acoustic load than ever before. But a question keeps coming up in clinics, classrooms, and conversations around ear health: Are earbuds worse for your hearing than over-ear headphones? Let’s move beyond opinion and aesthetics. By looking at sound pressure levels , hygiene , and long-term listening behaviour , we can reach a clear, evidence-informed conclusion. 1. Sound Pressure Levels: Distance Matters More Than You Think The single most important factor in headphone-related hearing risk is the amount of sound energy that  reaches the inner ear . Earbuds (In-Ear Headphones) Sit millimetres from the eardrum Deliver sound directly into the ear canal Require lower absolute power , but often result in higher sound pressure at the cochlea Users tend to increase volume in noisy environments (commuting, g...

"Naseptin: Powerful Defence Against Nasal Bacteria!"

  Everything You Need to Know About Using Naseptin Nasal Cream   If you've been dealing with nasal issues, you may have come across Naseptin nasal cream as a potential solution. Whether you suffer from recurrent nasal infections (vestibulitis), nose bleeds or simply need some relief from nasal dryness, Naseptin can be a valuable aid. In this blog, we'll cover everything you need to know about using Naseptin nasal cream to ensure you get the best results from this trusted product.   Unlocking the Power of Naseptin Nasal Cream: A Guide to Its Versatile Uses   Naseptin nasal cream, a powerful ally in nasal health, holds the key to treating infections caused by staphylococcal bacteria. This versatile cream offers much more than meets the eye, and we're here to shed light on its incredible benefits! 🌟 👃 Kicking Nose Infections to the Curb: Say goodbye to those troublesome nose infections! Naseptin comes to the rescue, targeting staphylococcal bacteria and...

“Where Are Your Tonsils? Your Health’s First Line of Defence!”

  Where Are Your Tonsils Located?   Learn About Their Position and Importance for Your Health Have you ever wondered where your tonsils are and why their location is significant for your health? Let's explore the fascinating world of tonsils and understand their crucial role in your body's defence system. What Are Tonsils? Tonsils are two oval-shaped masses of lymphoid tissue located at the back of your throat. They are part of your immune system, which is a complex network of cells, tissues, and organs that work together to defend the body against harmful invaders. The tonsils are vital in protecting your body from infections. They are often referred to as the "first line of defence" because they are strategically positioned to catch and filter out germs that enter through your mouth or nose. Where Exactly Are They Located? Your tonsils are situated in the pharynx, just behind the soft palate. There are two tonsils, one on each side of your throat. If you open your ...

Is Ear Wax Removal Safe?

  What is ear wax? The ear canal has two zones, outer ear canal lined by skin having hair and sweat glands and inner ear canal containing only skin covering bone next to eardrum. Earwax, medically known as cerumen, is a mixture of sweat, secretions from the sebaceous gland and dead cells. Therefore, the amount of secretions you have in your ear wax can be of two major types, wet ear wax and dry ear wax. Why do some people have more ear wax problems/ build-up? The first thing to know is everyone makes wax, and some naturally more and some less. Secondly, the shape of the ear canal can predispose you to have more earwax problems. You may have a hairy ear canal or narrow ear canal, which can trap more than the usual amount of ear wax you produce. Thirdly, if produce ear wax which gets stuck to the ear canal, it becomes difficult to fall out. Some people may push ear wax in if they are using insert headphones, i.e. earpods, earplugs for noise reduction or swimming/hearing aids. What ar...

Is my dizziness due to vestibular migraine?

  What's a vestibular migraine? Vestibular migraine is also known as migraine-related dizziness, migraine with prominent vertigo or migrainous vertigo. Patients will have vertigo symptoms, dizziness or imbalance, and some migraine symptoms. It is vital to understand that not all vestibular migraine patients will have headaches as the main symptoms. So migraine symptoms can be any of these: headache with or without nausea and vomiting, sensitivity to sound or lights or motion sickness. Each episode can last for minutes to hours. What causes or triggers a vestibular migraine? A lot of factors can trigger a vestibular migraine attack. The most common trigger factors are stress and anxiety, poor sleep hygiene, fasting and dehydration, menstrual cycle and food such as chocolate, cheese and red wine. How is vestibular migraine diagnosed? Diagnosis of vestibular migraine solely depends on patients history of symptoms. It is beneficial to record his or her episode in a vertigo or dizziness...

"Don't Let Glue Ear Hold Your Child Back: 10 Smart Management Techniques You Need to Know!"

  Parenting Tips for Effectively Managing Glue Ear in Children     Glue ear, also known as otitis media with effusion, is a common condition among children where fluid builds up in the middle ear. It can lead to hearing difficulties and other related issues. As a parent, it's important to understand how to manage glue ear effectively to support your child's well-being. In this article, we will provide you with some valuable parenting tips to help you navigate this condition.   1.        Recognize the Signs and Symptoms: Be aware of the signs that your child may be experiencing glue ear. These can include hearing difficulties, speech delays, frequent ear infections, balance problems, and irritability. If you suspect glue ear, consult a healthcare professional for a proper diagnosis.   2.        Communication and Support: Maintain open and honest communication with your child about their hearing difficul...

Why do I get nose bleeds?

What is nose bleed or epistaxis? Inside of the nose is lined by mucosa which is very rich in blood vessels. One of the main functions of the nose is to humidify the air we breathe in and out.  Humidication is naturally achieved by mucous cells lining the nose. Blood vessels can become weak due to dryness, high pressure behind the vessels or hormonal changes. What are different kinds of nose bleeds? In simple terms, one can have an anterior nose bleed or posterior nose bleed. Anterior nose bleed is when most of the blood comes out through the nostril and some you spit out. Posterior nose bleed is when you spit most of the blood and little comes out through nostril. Why do children have nose bleeds? It is very common for children between 2 to 10 to have nose bleeds. Dry weather during summers and dry air indoors during winters due to heating tends to dry nasal mucosa. Dry nasal mucosa, in turns, makes it itchy for children to rub their nose and lead to...

Spotting Glue Ear In Child

  👂🧒 Is It Glue Ear? 🤔 How to Recognize the Signs in Your Child! 📣   👋 If you're wondering whether your child might have glue ear (otitis media with effusion), you're not alone. It's crucial to recognize the signs early for the best care. Here's a quick guide to help you out:      1️ ⃣ Frequent Ear Infections: If your child often suffers from ear infections that seem to linger or come back frequently, it could be a clue.   2️ ⃣ Hearing Difficulty: Does your child struggle to hear or frequently ask you to repeat yourself? Pay attention if they seem to have difficulty understanding conversations.   3️ ⃣ Speech and Language Development: Glue ear might affect your child's speech and language development. Look out for delays or changes in their ability to communicate.   4️ ⃣ Behavioural Changes: Notice any behavioural shifts? Frustration, irritability, or problems concentrating might be linked to hearing issues caused by glue ear. ...