Skip to main content

Featured post

Hearing Reconstruction Surgery After Chronic Ear Disease: What Patients Need to Know

  Hearing Reconstruction Surgery After Chronic Ear Disease: A Patient Guide Persistent ear infections and chronic ear disease can sometimes lead to long-term hearing problems. For some patients, damage to the delicate hearing structures inside the middle ear may occur gradually over many years. Modern ENT surgery can often improve hearing by repairing or reconstructing these damaged structures. Understanding the available treatment options helps patients make informed decisions about their care. This guide explains how chronic ear disease affects hearing, when reconstruction surgery may be considered, and what recovery involves. How does chronic ear disease cause hearing loss? The middle ear contains three tiny hearing bones, known as the ossicles, which help transmit sound from the eardrum to the inner ear. Conditions such as: Recurrent ear infections Chronic perforated eardrum Cholesteatoma Previous ear surgery Long-standing inflammation can damage these delicate struc...

Why Some People Can't Stop Coughing

 



Understanding Refractory Chronic Cough: What You Need to Know

 

Have you ever faced a cough that simply refuses to subside?

 

While most coughs resolve independently, some persist for an unacceptable length of time—weeks, months, or even years. This condition is known as refractory chronic cough (RCC), and it is a significant issue that demands attention in the medical community, especially among specialists in ear, nose, and throat (ENT) care.

 

In this blog post, we will clearly outline what RCC is, why it occurs, and the most promising treatments available to those suffering from relentless coughing.

  

What is Refractory Chronic Cough?

 

A chronic cough is defined as one that lasts longer than eight weeks in adults. For many individuals, it is associated with conditions such as asthma, allergies, acid reflux, or certain medications. However, there are instances where the cough continues even after these underlying causes have been effectively addressed.

 This persistent and unexplained coughing is referred to as refractory chronic cough (RCC), which impacts as many as 46% of patients referred to specialists. RCC is not just a nuisance; it can severely disrupt breathing, interfere with daily activities, degrade sleep quality, and hinder social interactions.

 

It is critical for patients to seek appropriate evaluation and treatment for this distressing condition.

Why Does RCC Happen?

Coughing is a natural reflex that helps clear irritants from our airways. However, in RCC, this reflex becomes overly sensitive, causing a person to cough even when there’s no real need to. Researchers believe that both the nerves in the throat and the brain’s response to cough signals play a role in this hypersensitivity. Factors such as airway inflammation, nerve dysfunction, and central sensitization (similar to chronic pain conditions) can contribute to RCC. Additionally, exposure to pollutants, infections, or prior respiratory illnesses can make the airway more susceptible to developing RCC.


Symptoms and Impact of RCC

People with RCC often experience persistent coughing fits triggered by talking, laughing, exposure to certain smells, or temperature changes. The condition can lead to complications such as voice strain, throat pain, headaches, sleep disturbances, and even urinary incontinence due to the repetitive pressure from coughing. The social impact can also be significant, as people may avoid public places due to embarrassment or discomfort caused by their persistent cough.

New Advances in RCC Treatment

  1. Neuromodulators – Medications like amitriptyline and gabapentin help calm overactive nerves that trigger chronic coughing. Studies show that these drugs can significantly reduce symptoms in many patients. However, they may cause side effects such as drowsiness and dizziness, so careful dosage adjustments are needed.
  2. Superior Laryngeal Nerve (SLN) Block – This involves injecting a local anesthetic and steroid near a key nerve in the throat. It has shown promising results in reducing cough severity and frequency, with some patients experiencing relief lasting several months.
  3. Behavioral Cough Suppression Therapy (BCST) – Speech therapists teach patients techniques to control their cough reflex, including breathing exercises, vocal hygiene, and habit reversal strategies. Many people experience lasting improvement after therapy. This approach is particularly beneficial because it does not involve medication, making it a safer option for many patients.
  4. Capsaicin Therapy – Surprisingly, exposure to capsaicin (the compound that makes chili peppers spicy) in controlled doses can help desensitize the cough reflex over time. This method is still being studied, but early results suggest it may be effective in reducing cough hypersensitivity.
  5. Laryngopharyngeal Reflux (LPR) Management – Since acid reflux can contribute to RCC, new treatments like alginate therapy (which forms a protective barrier in the stomach) are being explored alongside traditional acid-reducing medications. Lifestyle changes, such as dietary modifications and avoiding late-night meals, can also help manage reflux-related cough.
  6. P2X3 Antagonists – A new class of medications targeting the P2X3 receptor, which is involved in the cough reflex, is being studied. Early trials have shown that these drugs may help reduce RCC symptoms, providing another potential treatment avenue.

What This Means for You


Coughing is a natural reflex that helps clear irritants from our airways. However, in RCC, this reflex becomes overly sensitive, causing a person to cough even when there’s no real need to. Researchers believe that both the nerves in the throat and the brain’s response to cough signals play a role in this hypersensitivity. Factors such as airway inflammation, nerve dysfunction, and central sensitization (similar to chronic pain conditions) can contribute to RCC. Additionally, exposure to pollutants, infections, or prior respiratory illnesses can make the airway more susceptible to developing RCC.

People with RCC often experience persistent coughing fits triggered by talking, laughing, exposure to certain smells, or temperature changes. The condition can lead to complications such as voice strain, throat pain, headaches, sleep disturbances, and even urinary incontinence due to the repetitive pressure from coughing. The social impact can also be significant, as people may avoid public places due to embarrassment or discomfort caused by their persistent cough.


The good news is that doctors are finding better ways to treat RCC. Here are some of the latest approaches:


If you or someone you know has a chronic cough that doesn’t improve with standard treatments, it’s important to see a specialist. ENT doctors and pulmonologists (chest physicians) now have a growing range of options to help manage RCC. The key is to undergo a thorough evaluation to rule out underlying conditions and explore the best treatment plan tailored to individual needs.

With ongoing research, treatment for refractory chronic cough is becoming more effective, improving the quality of life for many patients. By spreading awareness about RCC, we can help those affected find the relief they need.


Have you dealt with a persistent cough? Share your experience in the comments below!


Mr Gaurav Kumar

Consultant Ear Nose Throat Surgeon


Book Appointment

Book Online


07494914140




Follow on Instagram










Popular Post

Coblation Tonsillectomy

Hi Guys, Let us talk about your tonsils and adenoids. Tonsils and adenoids are part of the immune system and help fight germs. Sometimes these tissues become infected and is called tonsillitis. When you have tonsillitis, you can feel sore to eat and drink, have the temperature, and can even have difficulty in breathing. This can be treated by a procedure called Tonsillectomy. Mr Kumar may advise you to have your tonsils removed if you have tonsil stones, if your airway is blocked due to large tonsils making you choke at night ie sleep apnoea or one tonsil is bigger than other. Tonsillectomy can be done by the traditional techniques using cold steel, electrocautery or coblation.  Cold steel and elctrocautery has moderate to severe pain in postoperative period. With new coblation technique, post operative pain is very low leading to quicker recovery.  Coblation is an advanced technology that combines gentle radiofrequency energy with natural saline — to quickly, and safely r...

After your Epley manoeuvre — patient information leaflet

  What this leaflet tells you This leaflet explains what to expect after the Epley (canalith repositioning) manoeuvre for posterior-canal BPPV, what you should and shouldn’t do, and when to seek help.   1. Quick summary — what the Epley did The manoeuvre moves tiny particles (otoconia) out of the balance canal of your inner ear and back into a place where they don’t cause spinning (vertigo). Most people feel much better after one or a few treatments. However BPPV can come back (recurrence is common).   2. How you may feel immediately afterwards You may feel dizzy or off-balance for a few minutes to a few hours; nausea is possible.   Some people feel better straightaway; others get gradual improvement over days.   Rarely ,you may have brief recurrences of vertigo — this does not always mean the manoeuvre failed.   3. Activity and posture — what the evidence says Good news: High-quality studies and recent guidelines show that strict he...

Earbuds vs Over-Ears: Which One Is Silently Damaging Your Hearing?

Headphones are no longer an occasional accessory—they’re part of daily life. From early-morning podcasts to late-night playlists, our ears are spending more time under acoustic load than ever before. But a question keeps coming up in clinics, classrooms, and conversations around ear health: Are earbuds worse for your hearing than over-ear headphones? Let’s move beyond opinion and aesthetics. By looking at sound pressure levels , hygiene , and long-term listening behaviour , we can reach a clear, evidence-informed conclusion. 1. Sound Pressure Levels: Distance Matters More Than You Think The single most important factor in headphone-related hearing risk is the amount of sound energy that  reaches the inner ear . Earbuds (In-Ear Headphones) Sit millimetres from the eardrum Deliver sound directly into the ear canal Require lower absolute power , but often result in higher sound pressure at the cochlea Users tend to increase volume in noisy environments (commuting, g...

"Naseptin: Powerful Defence Against Nasal Bacteria!"

  Everything You Need to Know About Using Naseptin Nasal Cream   If you've been dealing with nasal issues, you may have come across Naseptin nasal cream as a potential solution. Whether you suffer from recurrent nasal infections (vestibulitis), nose bleeds or simply need some relief from nasal dryness, Naseptin can be a valuable aid. In this blog, we'll cover everything you need to know about using Naseptin nasal cream to ensure you get the best results from this trusted product.   Unlocking the Power of Naseptin Nasal Cream: A Guide to Its Versatile Uses   Naseptin nasal cream, a powerful ally in nasal health, holds the key to treating infections caused by staphylococcal bacteria. This versatile cream offers much more than meets the eye, and we're here to shed light on its incredible benefits! 🌟 👃 Kicking Nose Infections to the Curb: Say goodbye to those troublesome nose infections! Naseptin comes to the rescue, targeting staphylococcal bacteria and...

Is Ear Wax Removal Safe?

  What is ear wax? The ear canal has two zones, outer ear canal lined by skin having hair and sweat glands and inner ear canal containing only skin covering bone next to eardrum. Earwax, medically known as cerumen, is a mixture of sweat, secretions from the sebaceous gland and dead cells. Therefore, the amount of secretions you have in your ear wax can be of two major types, wet ear wax and dry ear wax. Why do some people have more ear wax problems/ build-up? The first thing to know is everyone makes wax, and some naturally more and some less. Secondly, the shape of the ear canal can predispose you to have more earwax problems. You may have a hairy ear canal or narrow ear canal, which can trap more than the usual amount of ear wax you produce. Thirdly, if produce ear wax which gets stuck to the ear canal, it becomes difficult to fall out. Some people may push ear wax in if they are using insert headphones, i.e. earpods, earplugs for noise reduction or swimming/hearing aids. What ar...

Otitis Externa and Otinova

  Otitis Externa and Otinova: A Practical, No-Nonsense Guide If your ear suddenly feels itchy, sore, blocked, or painful after swimming or showering, you may be dealing with otitis externa —often called “swimmer’s ear.” The good news: most cases are very treatable with the right early steps. This guide explains what otitis externa is, why it happens, where Otinova fits in, and when to escalate quickly. What is otitis externa? Otitis externa is inflammation (and sometimes infection) of the skin lining the external ear canal. It commonly presents with: Ear pain (often worse when touching or pulling the outer ear) Itching Fullness/blockage Reduced hearing from swelling/debris Sometimes watery discharge Otinova’s own instruction documents describe it as treatment for ear canal inflammation/eczema (swimmer’s ear). Why does it happen? The ear canal is protected by a mildly acidic environment and a skin barrier. Otitis externa tends to flare ...

Superior Canal Dehiscence Syndrome (SCDS)

🔍 Unlocking the Mystery of Superior Canal Dehiscence Syndrome (SCDS) 🌀✨ It's a rare condition that affects the inner ear, and here's the lowdown:   Cause: SCDS occurs when one of the bony canals in the inner ear, particularly the uppermost semicircular canal, doesn't close or thicken properly during fetal development.   Symptoms:   Hearing Loss: It's a common symptom of SCDS. Sound Distortion: Ever feel like sounds aren't quite right? That could be SCDS at play. Balance Problems: SCDS can throw your balance off, making you feel unsteady. Autophony: Imagine hearing your own heartbeat or breathing louder than usual. That's autophony. World Tumbling Sensation: Loud noises or pressure changes might make you feel like the world is spinning. Diagnosis and Treatment:   CT Scans: A specialist might use these to spot SCDS, but other tests are crucial too. Hearing Tests: Essential for accurate diagnosis. Treatment: Surgery may be necessary for severe symptoms. ...

Do I need nasal valve collapse surgery?

  What is the nasal valve area in the nose? The nose is a non-uniform tubular structure from the inside. The narrowest points are the entry point, the nostrils, and the exit point at the nose's back. As the nasal valve is the narrowest point, it plays a critical role in how we breathe. The nasal valve area is the internal nose area we can view without instruments when we look in the mirror with the head tilted back. Why is the nasal valve important in breathing through the nose? Airflow in the nasal valve area follows Bernoulli's principle. When the airflow increases, the pressure falls and pulls the side walls with it. This is very similar to when a fast train pulls the air around it with it. As a result, people on the platform are advised to stand clear because there is a risk of getting pulled in. How do I test if I have nasal valve collapse? Nasal valve problems can be due to bent septum or weak cartilages in the nose's sidewall. Using Breathe Easy Strips can give you a...

“Where Are Your Tonsils? Your Health’s First Line of Defence!”

  Where Are Your Tonsils Located?   Learn About Their Position and Importance for Your Health Have you ever wondered where your tonsils are and why their location is significant for your health? Let's explore the fascinating world of tonsils and understand their crucial role in your body's defence system. What Are Tonsils? Tonsils are two oval-shaped masses of lymphoid tissue located at the back of your throat. They are part of your immune system, which is a complex network of cells, tissues, and organs that work together to defend the body against harmful invaders. The tonsils are vital in protecting your body from infections. They are often referred to as the "first line of defence" because they are strategically positioned to catch and filter out germs that enter through your mouth or nose. Where Exactly Are They Located? Your tonsils are situated in the pharynx, just behind the soft palate. There are two tonsils, one on each side of your throat. If you open your ...

Hoarseness or change in voice...

When should I get worried about my change in voice? Change in voice can be due to so many causes. It can be due to simple things like acid reflux, chronic cough, flu, post nasal drip leading to frequent throat clearing or due to cancer on the voice box.  "IF YOU HAVE CHANGE IN VOICE WHICH IS GETTING WORSE FOR MORE THAN 3 WEEKS, YOU NEED TO SEE AN ENT SURGEON." Other symptoms which can be present with a change in voice in cases of laryngeal cancer be weight loss when you are not dieting, a lump in the throat, earache, shortness of breath, throat pain. How does the ENT surgeon diagnose what is causing my hoarseness? Change is voice can be due to both non-cancer and cancerous reasons. On a visit to ENT voice specialist, he or she will take a full detailed history, access how your profession is affecting your voice and how voice change is affecting your job. After recording your quality of sound, an endoscope (a thin tube with a camera attached) is used to ...